ERVK-6 Antibodies

AND ERVK-6 ELISA kits, ERVK-6 Proteins

Many biological assays use antibodies to detect ERVK-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ERVK-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ERVK-6 antibodies...

We validate the specificity of these antibodies to ERVK-6 by testing them on tissues known to express ERVK-6 positively and negatively. Browse below to find the ERVK-6 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ERVK-6 Infographic by Boster Bio

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ERVK-6 Overview

Facts about Endogenous retrovirus group K member 6 Rec protein.

ERVK-6 3D structure. Source: alphafold

Endogenous retrovirus group K member 6 Rec protein (ERVK-6)

Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the first genomic transcript. Rec interacts with a highly structured RNA element (RcRE) within the viral 3'LTR and recruits the cellular nuclear export machinery.

This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts. .

Gene Information

Human
Gene Name:	ERVK-6
Uniprot:	Q69383
Entrez:	64006

Family

Belongs to:

No superfamily

Alternative Names

Endogenous retrovirus group K member 6 Rec protein

Molecular Weight

Mass (kDA):
11.828 kDA

Genomic Context


Human

Location:	7p22.1
Sequence:	7;

Tissue Specificity

Expressed at higher level in placenta, expressed at lower level in several organs and cell lines.

Subcellular Localizations

Cytoplasm. Nucleus, nucleolus. Shuttles between the nucleus and the cytoplasm. When in the nucleus, resides in the nucleolus.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ERVK-6

References

PMID: 7983704 by Loewer R., et al. Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K.

PMID: 10469592 by Barbulescu M., et al. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.