- Table of Content
ESXR1-N functions as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' that is present within the first intron of the KRAS gene and inhibits its expression.
|Sequence:||X; NC_000023.11 (104250038..104254933, complement)|
Expressed in placenta and testis. Expressed in testicular germ cell tumors.
Cytoplasm. Nucleus. ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm.