Extended synaptotagmin-3 Antibodies

AND ESYT3 ELISA kits, Extended synaptotagmin-3 Proteins

Many biological assays use antibodies to detect Extended synaptotagmin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Extended synaptotagmin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Extended synaptotagmin-3 antibodies...

We validate the specificity of these antibodies to Extended synaptotagmin-3 by testing them on tissues known to express ESYT3 positively and negatively. Browse below to find the ESYT3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ESYT3 Infographic by Boster Bio

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FAM62C (ESYT3) (NM_031913) Human Over-expression Lysate

Human

$960
Cat # LS083850
20 µg, 100 µg

ESYT3 Overview

Facts about Extended synaptotagmin-3.

ESYT3 3D structure. Source: alphafold

Extended synaptotagmin-3 (ESYT3)

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.

Gene Information

Human
Gene Name:	ESYT3
Uniprot:	A0FGR9
Entrez:	83850

Family

Belongs to:

extended synaptotagmin family

Alternative Names

chr3 synaptotagmin; CHR3SYT; extended synaptotagmin-like protein 3; member C

Molecular Weight

Mass (kDA):
100.035 kDA

Genomic Context


Human

Location:	3q22.3
Sequence:	3; NC_000003.12 (138434573..138481686)

Tissue Specificity

Widely expressed with high level in cerebellum and skin.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:29469807, PubMed:30220461). Recruited to the cell membrane via the third C2 domain.

Diseases

Hypertensive Disease
Obesity
Hyperlipidemia
Diabetes Mellitus
Coronary Artery Disease

Interacting Proteins

ESYT1
ESYT2

Pathways

Pathogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ESYT3

References

PMID: 17360437 by Min S.-W., et al. E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains.

PMID: 11543631 by Craxton M.A.; Genomic analysis of synaptotagmin genes.