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- Table of Contents
EXD1 Antibodies
AND EXD1 ELISA kits, EXD1 Proteins
Many biological assays use antibodies to detect EXD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EXD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EXD1 antibodies...
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EXD1 Infographic by Boster Bio
All EXD1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, WB
$523
Cat # M15906-1
100 µl
Cat # M15906-1
100 µl
Human, Monkey, Rat
Flow Cytometry, WB
$523
Cat # M15906
100 µl
Cat # M15906
100 µl
EXD1 Overview
Facts about piRNA biogenesis protein EXD1.
piRNA biogenesis protein EXD1 (EXD1)
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is vital for the germline integrity (By similarity).
The PET complex is required through the secondary piRNAs metabolic process for the PIWIL2 cutting - triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 likely acts as an RNA adapter.
Gene Information
| Human | |
|---|---|
| Gene Name: | EXD1 |
| Uniprot: | Q8NHP7 |
| Entrez: | 161829 |
Family
| Belongs to: |
|---|
| EXD1 family |
Alternative Names
EXDL1; exonuclease 3'-5' domain containing 1; exonuclease 3'-5' domain-containing protein 1; exonuclease 3'-5' domain-like 1; Exonuclease 3'-5' domain-like-containing protein 1; MGC33637
Molecular Weight
Mass (kDA):
58.335 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q15.1 |
| Sequence: | 15; NC_000015.10 (41182728..41231074, complement) |
Subcellular Localizations
Cytoplasm. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
Interacting Proteins
- EML2
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EXD1
bosterbio.com/bosterbio-gene-info-cards/EXD1
References
PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.
PMID: 16572171 by Zody M.C., et al. Analysis of the DNA sequence and duplication history of human chromosome 15.