EXOC2 Antibodies

AND EXOC2 ELISA kits, EXOC2 Proteins

Many biological assays use antibodies to detect EXOC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EXOC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EXOC2 antibodies...

We validate the specificity of these antibodies to EXOC2 by testing them on tissues known to express EXOC2 positively and negatively. Browse below to find the EXOC2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: PRR11

EXOC2 Infographic by Boster Bio

All EXOC2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

EXOC2 (NM_018303) Human Over-expression Lysate

Human

$628
Cat # LS055770
20 µg, 100 µg

Anti-EXOC2 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Western blot analysis of EXOC2 expression in BxPC-3 cell lysate

Human, Mouse, Rat

$370
Cat # M04913
100 µl/vial

Anti-SEC5/EXOC2 Antibody Picoband®

Western blot analysis of SEC5/EXOC2 using anti-SEC5/EXOC2 antibody (A04913-2)

IHC analysis of SEC5/EXOC2 using anti-SEC5/EXOC2 antibody (A04913-2)

IF analysis of SEC5/EXOC2 using anti-SEC5/EXOC2 antibody (A04913-2) and anti-Alpha Tubulin antibody (M03989-3)

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04913-2
100 μg/vial

EXOC2 Overview

Facts about Exocyst complex component 2.

EXOC2 3D structure. Source: alphafold

Exocyst complex component 2 (EXOC2)

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. .

Gene Information

Human
Gene Name:	EXOC2
Uniprot:	Q96KP1
Entrez:	55770

Family

Belongs to:

SEC5 family

Alternative Names

exocyst complex component 2; Exocyst complex component Sec5; FLJ11026; SEC5; SEC5L1; SEC5-like 1 (S. cerevisiae); SEC5-like 1; Sec5p

Molecular Weight

Mass (kDA):
104.066 kDA

Genomic Context


Human

Location:	6p25.3
Sequence:	6; NC_000006.12 (485138..693141, complement)

Tissue Specificity

Widely expressed with highest levels in brain and placenta.

Subcellular Localizations

Midbody, Midbody ring. Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Skin Neoplasms
Carcinoma
Innate Immune Response
Malignant Squamous Cell Neoplasm
Complete Hearing Loss
Skin Carcinoma
Basal Cell Carcinoma
Neoplasm Metastasis
Squamous Cell Carcinoma Of Skin

Melanoma
Sting Injury
Tumor Progression
Bone Neoplasms
Malignant Neoplasm Of Urinary Bladder
Metastatic Malignant Neoplasm To The Bone
Pancreatic Neoplasm

Interacting Proteins

EXOC1

Pathways

Secretion
Exocytosis
Transport
Exocyst Assembly
Pigmentation
Cell Proliferation
Endocytosis
Pathogenesis
Cell Migration
Cytokine Secretion
Immune Response
Response To Virus
Cytokinesis

Innate Immune Response
Glucose Transport
Oncogenesis
Vesicle Transport
Entry Into Host
Membrane Fusion
Abscission

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EXOC2

References

PMID: 12459492 by Sjoelinder M., et al. DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.

PMID: 16213214 by Gromley A., et al. Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.