This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Eef2k Antibodies
AND Eef2k ELISA kits, Eef2k Proteins
Many biological assays use antibodies to detect Eef2k, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Eef2k in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Eef2k antibodies...
Designing a Western blot for Eef2k? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EEF2K Western Blot GuideEef2k Infographic by Boster Bio
All Eef2k Products
Product
Figures
Specificity
Applications
Price
Human, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02277-3
100 μg/vial
Cat # A02277-3
100 μg/vial
Human, Rat
ELISA
$540
Cat # EKC1986
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1986
1 kit, containing two 96-well plates and all necessary reagents
Human, Rat
ELISA
$480
Cat # EKC1181
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1181
1 kit, containing one 96-well plate and all necessary reagents
Eef2k Overview
Facts about Eukaryotic elongation factor 2 kinase.
Eukaryotic elongation factor 2 kinase (Eef2k)
Threonine kinase that modulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single website, renders it unable to bind ribosomes and thus inactive.
Subsequently, the rate of protein synthesis is decreased. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Eef2k |
| Uniprot: | O08796 |
| Entrez: | 13631 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; EC 2.7.11; EC 2.7.11.20; eEF-2 kinase; eEF-2Kcalmodulin-dependent protein kinase III; elongation factor-2 kinase; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; MGC45041
Molecular Weight
Mass (kDA):
81.739 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 F2 |
| Sequence: | 7; |
Tissue Specificity
Ubiquitously expressed. Particularly abundant in skeletal muscle and heart.
Diseases
- Malignant Neoplasms
- Neoplasms
- Glioma
- Hypertrophy
- Glioblastoma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Hypoxia
- Physiological Stress
- Cell Transformation, Neoplastic
- Hyperplasia
- Sclerosis
- Cardiac Hypertrophy
Pathways
- Translation
- Cell Proliferation
- Cell Cycle
- Autophagy
- Protein Phosphorylation
- Cell Death
- Regulation Of Translation
- Rna Interference
- Energy Homeostasis
- Cell Growth
- Response To Nutrient
- Oncogenesis
- Mitosis
PTMs
- Phosphorylation
- Dephosphorylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Eef2k
bosterbio.com/bosterbio-gene-info-cards/Eef2k
References
PMID: 9144159 by Ryazanov A.G., et al. Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.