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- Table of Contents
Protein enabled homolog Antibodies
AND Enah ELISA kits, Protein enabled homolog Proteins
Many biological assays use antibodies to detect Protein enabled homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein enabled homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein enabled homolog antibodies...
Designing a Western blot for Protein enabled homolog? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ENAH Western Blot GuideDesigning an IHC experiment for Protein enabled homolog? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ENAH IHC GuideEnah Infographic by Boster Bio
All Enah Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A05337-2
100 μg/vial
Cat # A05337-2
100 μg/vial
Enah Overview
Facts about Protein enabled homolog.
Protein enabled homolog (Enah)
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity like axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin wealthy outgrowths in fibroblasts.
Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Enah |
| Uniprot: | Q03173 |
| Entrez: | 13800 |
Family
| Belongs to: |
|---|
| Ena/VASP family |
Alternative Names
ENA; enabled homolog (Drosophila); ENAH; FLJ10773; Mena; MENANDPP1; NDPP1; protein enabled homolog
Molecular Weight
Mass (kDA):
85.844 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 1 H5|1 84.93 cM |
| Sequence: | 1; |
Tissue Specificity
Expressed in heart and testis, lower levels in lung, skeletal muscle, kidney, pancreas and brain. Isoform 5 is expressed exclusively in the brain. Isoform 2 is expressed predominantly in brain, testis, ovary and fat. In the brain, isoforms 2 and 5 are expressed at highest levels in the hippocampus, cortex and midbrain, and at lowest levels in the striatum and cerebellum. Isoform 6 is expressed in brain and spleen.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Carcinoma
- Neoplasm Invasiveness
- Protrusion
- Adenocarcinoma
- Carcinogenesis
- Metastatic Malignant Neoplasm To The Lung
Pathways
- Cell Motility
- Cell Migration
- Cell Adhesion
- Regulation Of Cell Motility
- Localization
- Axon Guidance
- Wound Healing
- Cell-cell Adhesion
- Cell Proliferation
- Rna Interference
- Immune Response
- Platelet Activation
- Platelet Aggregation
PTMs
- Phosphorylation
Research Areas
- Cancer
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Enah
bosterbio.com/bosterbio-gene-info-cards/Enah
References
PMID: 1420303 by Sazuka T., et al. Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein.
PMID: 8861907 by Gertler F.B., et al. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics.