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- Table of Contents
F13A1 Antibodies
AND F13A1 ELISA kits, F13A1 Proteins
Many biological assays use antibodies to detect F13A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F13A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F13A1 antibodies...
Designing a Western blot for F13A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the F13A1 Western Blot GuideF13A1 Infographic by Boster Bio
All F13A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, WB
$370
Cat # A02047-1
100 μg/vial
Cat # A02047-1
100 μg/vial
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02047-1
100 μl
Cat # M02047-1
100 μl
F13A1 Overview
Facts about Coagulation factor XIII A chain.
Coagulation factor XIII A chain (F13A1)
Factor XIII is activated by thrombin and calcium ion to a transglutaminase which catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Additionally cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
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Gene Information
| Human | |
|---|---|
| Gene Name: | F13A1 |
| Uniprot: | P00488 |
| Entrez: | 2162 |
Family
| Belongs to: |
|---|
| transglutaminase superfamily |
Alternative Names
bA525O21.1 (coagulation factor XIII, A1 polypeptide); coagulation factor XIII A chain; coagulation factor XIII, A1 polypeptide; Coagulation factor XIIIa; EC 2.3.2.13; F13A; F13A1; F13Acoagulation factor XIII, A polypeptide; factor XIIIa; fibrin stabilizing factor, A subunit; fibrinoligase; FSF, A Subunit; Protein-glutamine gamma-glutamyltransferase A chain; TGase; Transglutaminase A chain; transglutaminase. plasma
Molecular Weight
Mass (kDA):
83.267 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p25.1 |
| Sequence: | 6; NC_000006.12 (6144084..6320662, complement) |
Subcellular Localizations
Cytoplasm. Secreted. Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Diseases
- Cleft Lip
- Cleft Palate
- Factor Xiii Deficiency
- Blood Coagulation Disorders
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Infarction
- Inflammation
- Ataxia
- Ataxia, Spinocerebellar
- Variable Number Tandem Repeat
- Myocardial Infarction
- Thrombosis
Pathways
- Coagulation
- Blood Coagulation
- Pathogenesis
- Fibrinolysis
- Cell Adhesion
- Endochondral Bone Growth
- Endochondral Ossification
- Dna Hypomethylation
- Complement Activation
- Metaphase
- Regulation Of Gene Expression
- Ossification
- Chondrocyte Hypertrophy
PTMs
Research Areas
- Apoptosis
- Cancer
- Cell Biology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F13A1
bosterbio.com/bosterbio-gene-info-cards/F13A1
References
PMID: 3026437 by Ichinose A., et al. Amino acid sequence of the a subunit of human factor XIII.
PMID: 2877457 by Grundmann U., et al. Characterization of cDNA coding for human factor XIIIa.