FARP1 Antibodies

AND FARP1 ELISA kits, FARP1 Proteins

Many biological assays use antibodies to detect FARP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FARP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FARP1 antibodies...

We validate the specificity of these antibodies to FARP1 by testing them on tissues known to express FARP1 positively and negatively. Browse below to find the FARP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FARP1 Infographic by Boster Bio

All FARP1 Products

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FARP1 (NM_005766) Human Recombinant Protein

Coomassie blue staining of purified FARP1 protein

$1249
Cat # PROTQ9Y4F1
20 µg

FARP1 (NM_005766) Human Over-expression Lysate

FARP1 Human Over-expression Lysates NM_001001715

Human

$628
Cat # LS010160
20 µg, 100 µg

FARP1 Overview

Facts about FERM, ARHGEF and pleckstrin domain-containing protein 1.

FARP1 3D structure. Source: alphafold

FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1)

Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling.

Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). .

Gene Information

Human
Gene Name:	FARP1
Uniprot:	Q9Y4F1
Entrez:	10160

Family

Belongs to:

No superfamily

Alternative Names

CDEPPleckstrin homology domain-containing family C member 2; Chondrocyte-derived ezrin-like protein; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; MGC87400; PLEKHC2PH domain-containing family C member 2

Molecular Weight

Mass (kDA):
118.633 kDA

Genomic Context


Human

Location:	13q32.2
Sequence:	13; NC_000013.11 (98142589..98455176)

Tissue Specificity

Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung.

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome. Cytoplasm, cytosol. Cell projection, filopodium. Cell projection, dendrite. Cell projection, dendritic spine. Recruited to the cell membrane via interaction with CADM1.

Diseases

Tissue Adhesions
Monosomy
Somatotropin Deficiency
Dystrophy
Autistic Disorder
Corneal Diseases
Gilles De La Tourette Syndrome
Cerebrovascular Accident
Migraine Disorders

Growth Disorders
Congenital Hand Deformities
Embryonic Mosaic
Muscular Dystrophy

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FARP1

References

PMID: 9425278 by Koyano Y., et al. Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of rho guanine nucleotide exchange factors.

PMID: 23375260 by He X., et al. Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2.