Many biological assays use antibodies to detect FAS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FAS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FAS antibodies...
We validate the specificity of these antibodies to FAS by testing them on tissues known to express FAS positively and negatively. Browse below to find the FAS antibody that suites your experiment. We have 99 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Designing a Western blot for FAS?
The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
$499 Cat # FEK1255 96 wells/kit, with removable strips.
FAS Overview
Facts about Tumor necrosis factor receptor superfamily member 6.
Tumor necrosis factor receptor superfamily member 6 (FAS)
Receptor for TNFSF6/FASLG.
The adapter molecule FADD recruits caspase-8 to the activated receptor.
The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of older T-cells, or both.
Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.
For details, visit: bosterbio.com/bosterbio-gene-info-cards/FAS
References
PMID: 1713127 by Itoh N., et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
PMID: 1375228 by Oehm A., et al. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.
19 Publications of Boster FAS Antibodies & ELISA Kits
PubMed ID: 10.1002/cbin.11490, Fat mass and obesity‐associated protein regulates lipogenesis via m6A modifica...
PubMed ID: 20026302 , Expression of the hGM-CSF in the silk glands of germline of gene-targeted silkwo...
PubMed ID: 28250578, Oral Administration of Resveratrol Alleviates Osteoarthritis Pathology in C57BL/...
PubMed ID: 26789107, Puerarin Protects Pancreatic ?-Cells in Obese Diabetic Mice via Activation of GL...
PubMed ID: 26305254, Apple Polyphenols Decrease Atherosclerosis and Hepatic Steatosis in ApoE?/? Mice...
PubMed ID: 25450719, Dietary effects on liver tumor burden in mice treated with the hepatocellular ca...
PubMed ID: 29044029, Altay C, Se?il M, Demir T, Atik T, Ak?nc? G, ?zdemir Kutbay N, Keskin Temelo?lu ...
PubMed ID: 29512890, Zou J, Wang N, Liu M, Bai Y, Wang H, Liu K, Zhang H, Xiao X, Wang K. J Cell Mol ...
PubMed ID: 28645299, Chen, M., Wang, X., Hu, Z., Zhou, H., Xu, Y., Qiu, L.,…, & Ying, Z. (2017). Pr...
PubMed ID: 28443464, Lu C, Ma J, Cai D. Tumour Biol. 2017 Apr;39(4):1010428317697574. doi: 10.1177/10...
PubMed ID: 24936481, Hatami Zargaran Z, Salehi M, Heydari St, Babajafari S. Int Cardiovasc Res J. 201...
PubMed ID: 24986510, Liu Xx, Liu Ky, Li P, Han S, Peng Xd, Shen L. Diabetes Metab. 2014 Nov;40(5):363...
PubMed ID: 24194905, Chai Zt, Kong J, Zhu Xd, Zhang Yy, Lu L, Zhou Jm, Wang Lr, Zhang Kz, Zhang Qb, A...
PubMed ID: 26038476, Li L, Ben Y, Yuan S, Liu A, Wu H, Xu J, Zhang X. Emerg Microbes Infect. 2013 Jul...
PubMed ID: 22391529, Zhong M, He B, Yang J, Bao R, Zhang Y, Zhou D, Chen Y, Li L, Han C, Yang Y, Sun ...
PubMed ID: 25371737, Liu L, Gu H, Zhao Y, An L, Yang J. Exp Ther Med. 2014 Dec;8(6):1813-1818. Epub 2...
PubMed ID: 25802537, Wu Cc, Weng Wl, Lai Wl, Tsai Hp, Liu Wh, Lee Mh, Tsai Yc. Evid Based Complement ...
PubMed ID: 23786840, Xu R, Tao A, Zhang S, Zhang M. Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(...
PubMed ID: 25807257, Zhang H, Xia X, Han F, Jiang Q, Rong Y, Song D, Wang Y. Mol Pharm. 2015 May 4;12...
*More publications can be found for each product on its corresponding product page