Anti-Fas Antibody Picoband®

Product Name

Anti-Fas Antibody Picoband®

View all Fas Antibodies

SKU/Catalog Number

PA1119
BA0484 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Fas Antibody catalog # PA1119. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Fas Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1119)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of rat Fas.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1119 is reactive to Fas in Mouse, Rat

Observed Molecular Weight

12 kDa

Calculated molecular weight

36.8 kDa

Background of Fas

FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1119 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Mouse, Rat , -
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Positive Control

WB: rat liver extract, rat spleen extract, rat brain extract, rat cardiac muscle extract, mouse liver extract, mouse spleen extract, mouse brain extract, mouse kidney extract, mouse thymus extract, mouse lung extract, HEPA1-6 whole cell, NIH3T3 whole cell
IHC: Rat Spleen Tissue, mouse intestine tissue

Validation Images & Assay Conditions

See full target information Fas

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