FBLIM1 Antibodies

AND FBLIM1 ELISA kits, FBLIM1 Proteins

Many biological assays use antibodies to detect FBLIM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FBLIM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FBLIM1 antibodies...

We validate the specificity of these antibodies to FBLIM1 by testing them on tissues known to express FBLIM1 positively and negatively. Browse below to find the FBLIM1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBLIM1 Infographic by Boster Bio

All FBLIM1 Products

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Product

Figures

Specificity

Applications

Price

FBLIM1 (NM_017556) Human Recombinant Protein

Coomassie blue staining of purified FBLIM1 protein

$1249
Cat # PROTQ8WUP2
20 µg

Anti-FBLIM1 Mouse Monoclonal Antibody [Clone ID: OTI3G1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FBLIM1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-FBLIM1 monoclonal antibody at 1:200 dilution

Human

$523
Cat # M08050
100 µl

FBLIM1 (NM_017556) Human Over-expression Lysate

FBLIM1 Human Over-expression Lysates NM_001024215

Human

$628
Cat # LS054751
20 µg, 100 µg

Anti-FBLIM1 Antibody Picoband®

Western blot analysis of FBLIM1 using anti-FBLIM1 antibody (A08050-1)

Flow Cytometry analysis of U251 cells using anti-FBLIM1 antibody (A08050-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08050-1
100 μg/vial

FBLIM1 Overview

Facts about Filamin-binding LIM protein 1.

FBLIM1 3D structure. Source: alphafold

Filamin-binding LIM protein 1 (FBLIM1)

Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility.

May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly.

Gene Information

Human
Gene Name:	FBLIM1
Uniprot:	Q8WUP2
Entrez:	54751

Family

Belongs to:

No superfamily

Alternative Names

CAL; DKFZp434G171; FBLP-1FBLP1CSX-associated LIM; filamin binding LIM protein 1; filamin-binding LIM protein 1; filamin-binding LIM protein-1; MIG2-interacting protein; migfilin; mitogen-inducible 2 interacting protein; Mitogen-inducible 2-interacting protein

Molecular Weight

Mass (kDA):
40.67 kDA

Genomic Context


Human

Location:	1p36.21
Sequence:	1; NC_000001.11 (15756170..15786590)

Tissue Specificity

Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.

Subcellular Localizations

Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Associated with actin stress fiber at cell-ECM focal adhesion sites (PubMed:12679033, PubMed:18829455). Isoform 1 and isoform 3 are recruited and localized at actin stress fibers and clustered at cell-EMC adhesion sites through interaction with FERMT2 (PubMed:12679033). Isoform 2 is localized at actin stress fibers (PubMed:12496242).