Fibulin-5 (FBLN5)

Essential for elastic fiber formation, is involved in the fabrication of constant elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and arouses elastic fibers in the skin, lung and vasculature (By similarity).

Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which might play a role in vascular development and remodeling (PubMed:10428823).