FBXL7 Antibodies

AND FBXL7 ELISA kits, FBXL7 Proteins

Many biological assays use antibodies to detect FBXL7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FBXL7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FBXL7 antibodies...

We validate the specificity of these antibodies to FBXL7 by testing them on tissues known to express FBXL7 positively and negatively. Browse below to find the FBXL7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: FAM120A

FBXL7 Infographic by Boster Bio

All FBXL7 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

FBXL7 (NM_012304) Human Over-expression Lysate

Human

$628
Cat # LS023194
20 µg, 100 µg

FBXL7 Overview

Facts about F-box/LRR-repeat protein 7.

FBXL7 3D structure. Source: alphafold

F-box/LRR-repeat protein 7 (FBXL7)

Substrate recognition element of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest. .

Gene Information

Human
Gene Name:	FBXL7
Uniprot:	Q9UJT9
Entrez:	23194

Family

Belongs to:

FBXL7 family

Alternative Names

FBL7FBL6F-box protein Fbl7; F-box and leucine-rich repeat protein 7F-box protein FBL6/FBL7; F-box/LRR-repeat protein 7; KIAA0840

Molecular Weight

Mass (kDA):
54.575 kDA

Genomic Context


Human

Location:	5p15.1
Sequence:	5; NC_000005.10 (15500180..15939796)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to the centrosome during spindle formation.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Brca2 Gene Mutation
Neoplasm Metastasis
Neoplasms
Tetraploidy
Malignant Neoplasm Of Ovary
Mammary Neoplasms

Endometrial Polyp
Carcinoma

Pathways

Cell Proliferation
Mitosis
Interphase
Estrus
Insemination
Chromosome Segregation

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBXL7

References

PMID: 10945468 by Ilyin G.P., et al. cDNA cloning and expression analysis of new members of the mammalian F-box protein family.

PMID: 10531035 by Cenciarelli C., et al. Identification of a family of human F-box proteins.