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- Table of Contents
Designing an IHC experiment for FAM120A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the FAM120A IHC GuideFacts about Constitutive coactivator of PPAR-gamma-like protein 1.
Activates src family kinases and functions as a scaffolding protein allowing src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II.
| Human | |
|---|---|
| Gene Name: | FAM120A |
| Uniprot: | Q9NZB2 |
| Entrez: | 23196 |

| Belongs to: |
|---|
| constitutive coactivator of PPAR-gamma family |

C9orf10MGC133257; chromosome 9 open reading frame 10; constitutive coactivator of PPAR-gamma-like protein 1; DNA polymerase-transactivated protein 1; DNA polymerase-transactivated protein 5; DNAPTP1; DNAPTP5; family with sequence similarity 120A; KIAA0183MGC111527; OSSA; Oxidative stress-associated Src activator; Protein FAM120A
Mass (kDA):
121.888 kDA

| Human | |
|---|---|
| Location: | 9q22.31 |
| Sequence: | 9; NC_000009.12 (93451685..93566112) |
Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Translocates to plasma membrane upon ultraviolet exposure.


PMID: 14585507 by Holden S., et al. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34.
PMID: 19015244 by Tanaka M., et al. A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.