FBXW10 Antibodies

AND FBXW10 ELISA kits, FBXW10 Proteins

Many biological assays use antibodies to detect FBXW10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FBXW10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FBXW10 antibodies...

We validate the specificity of these antibodies to FBXW10 by testing them on tissues known to express FBXW10 positively and negatively. Browse below to find the FBXW10 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBXW10 Infographic by Boster Bio

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FBXW10 Overview

Facts about F-box/WD repeat-containing protein 10.

FBXW10 3D structure. Source: alphafold

F-box/WD repeat-containing protein 10 (FBXW10)

Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.

Gene Information

Human
Gene Name:	FBXW10
Uniprot:	Q5XX13
Entrez:	10517

Family

Belongs to:

No superfamily

Alternative Names

F-box and WD repeat domain containing 10; F-box protein; F-box/WD repeat-containing protein 10

Molecular Weight

Mass (kDA):
119.846 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (18744024..18779349)

Diseases

Abnormal Degeneration
Inflammation
Myositis

Pathways

Heterochromatin Organization
Localization
Nuclear Export

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBXW10

References

PMID: 15520277 by Jin J., et al. Systematic analysis and nomenclature of mammalian F-box proteins.

PMID: 20498703 by Chaturvedi P., et al. Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10.