Fcgr4 Antibodies

AND Fcgr4 ELISA kits, Fcgr4 Proteins

Many biological assays use antibodies to detect Fcgr4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fcgr4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fcgr4 antibodies...

We validate the specificity of these antibodies to Fcgr4 by testing them on tissues known to express Fcgr4 positively and negatively. Browse below to find the Fcgr4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Fcgr4 Infographic by Boster Bio

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Fcgr4 Overview

Facts about Low affinity immunoglobulin gamma Fc region receptor IV.

Fcgr4 3D structure. Source: alphafold

Low affinity immunoglobulin gamma Fc region receptor IV (Fcgr4)

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also functions as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059).

Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059).

Gene Information

Mouse
Gene Name:	Fcgr4
Uniprot:	A0A0B4J1G0
Entrez:	246256

Family

Belongs to:

No superfamily

Alternative Names

Low affinity immunoglobulin gamma Fc region receptor IV

Molecular Weight

Mass (kDA):
28.398 kDA

Genomic Context


Mouse

Location:	1 H3\|1 78.53 cM
Sequence:	1;

Tissue Specificity

Detected on myeloid cells, peripheral blood monocytes, splenic and bone marrow dendritic cells, and thioglycollate-elicited macrophages and neutrophils but absent from lymphoid populations with no expression observed on T cells, B cells, NK cells or other granulocytes (at protein level) (PubMed:16039578, PubMed:19795417). Expressed in peripheral blood leukocytes, spleen, liver, thymus and small intestine (PubMed:12389094, PubMed:17558411).

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fcgr4

References

PMID: 12389094 by Mechetina L.V., et al. Identification of CD16-2, a novel mouse receptor homologous to CD16/Fc gamma RIII.

PMID: 18292508 by Xiu Y., et al. B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.