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- Table of Contents
Facts about Fibronectin type III domain-containing protein 1.
.
| Human | |
|---|---|
| Gene Name: | FNDC1 |
| Uniprot: | Q4ZHG4 |
| Entrez: | 84624 |

| Belongs to: |
|---|
| No superfamily |

bA243O10.1; dJ322A24.1; expressed in synovial lining protein; fibronectin type III domain containing 1; fibronectin type III domain containing 2
Mass (kDA):
205.558 kDA

| Human | |
|---|---|
| Location: | 6q25.3 |
| Sequence: | 6; NC_000006.12 (159169400..159272108) |
Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.
Secreted.




PMID: 9704633 by Seki T., et al. Use of differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes.
PMID: 16098131 by Anderegg U., et al. MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF- beta and pro-inflammatory cytokines.