Forkhead box protein C2 Antibodies

AND FOXC2 ELISA kits, Forkhead box protein C2 Proteins

Many biological assays use antibodies to detect Forkhead box protein C2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein C2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein C2 antibodies...

We validate the specificity of these antibodies to Forkhead box protein C2 by testing them on tissues known to express FOXC2 positively and negatively. Browse below to find the FOXC2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Forkhead box protein C2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the FOXC2 Western Blot Guide

FOXC2 Infographic by Boster Bio

All FOXC2 Products

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Specificity

Applications

Price

Anti-FOXC2 Picoband® Antibody

Western blot analysis of FOXC2 using anti-FOXC2 antibody (A01780-2)

IF analysis of FOXC2 using anti-FOXC2 antibody (A01780-2) and anti-Tubulin Alpha antibody (M03989-3)

Flow Cytometry analysis of Hela cells using anti-FOXC2 antibody (A01780-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A01780-2
100 μg/vial

FOXC2 (NM_005251) Human Over-expression Lysate

Human

$960
Cat # LS002303
20 µg, 100 µg

FOXC2 Overview

Facts about Forkhead box protein C2.

FOXC2 3D structure. Source: alphafold

Forkhead box protein C2 (FOXC2)

Transcriptional activator. Might be involved in the creation of specific mesenchymal tissues.

Gene Information

Human
Gene Name:	FOXC2
Uniprot:	Q99958
Entrez:	2303

Family

Belongs to:

No superfamily

Alternative Names

Fkh14; FKHL14LD; forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead, Drosophila, homolog-like 14; Forkhead-related protein FKHL14; FoxC2; LD; Mesenchyme fork head protein 1; mesenchyme forkhead 1; MFH-1 protein; MFH1; MFH-1; MFH1forkhead box protein C2; Transcription factor FKH-14

Molecular Weight

Mass (kDA):
53.719 kDA

Genomic Context


Human

Location:	16q24.1
Sequence:	16; NC_000016.10 (86566829..86569728)

Subcellular Localizations

Nucleus.

Diseases

Lymphedema
Malignant Neoplasms
Neoplasms
Distichiasis-lymphedema Syndrome
Milroy Disease
Malignant Neoplasm Of Breast
Neoplasm Metastasis
Diabetes Mellitus
Tumor Angiogenesis
Obesity
Edema
Haploinsufficiency

Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Hyperplasia
Mammary Neoplasms
Congenital Abnormality
Cell Invasion
Tissue Adhesions

Interacting Proteins

RBPMS
TAX1BP1
TRIM27

Pathways

Angiogenesis
Lymphangiogenesis
Pathogenesis
Cell Adhesion
Localization
Cell Proliferation
Cell Migration
Aging
Cell Fate Determination
Wound Healing
Cell Differentiation
Transport
Tube Formation

Endothelial Cell Proliferation
Cell Cycle
Osteoblast Differentiation
Ossification
Somitogenesis
Notch Signaling Pathway
Endothelial Cell Migration

PTMs

Phosphorylation
Cleavage

Sumoylation
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FOXC2

References

PMID: 9169153 by Miura N., et al. Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures.

PMID: 11078474 by Fang J., et al. Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome.