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- Table of Contents
FRK Antibodies
AND FRK ELISA kits, FRK Proteins
Many biological assays use antibodies to detect FRK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRK antibodies...
Designing a Western blot for FRK? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FRK Western Blot GuideFRK Infographic by Boster Bio
All FRK Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A04075-1
100 μg/vial
Cat # A04075-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M04075-1
100 µl
Cat # M04075-1
100 µl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1722
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1722
1 kit, containing one 96-well plate and all necessary reagents
FRK Overview
Facts about Tyrosine-protein kinase FRK.
Tyrosine-protein kinase FRK (FRK)
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Gene Information
| Human | |
|---|---|
| Gene Name: | FRK |
| Uniprot: | P42685 |
| Entrez: | 2444 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
EC 2.7.10; Frk; fyn-related kinaseProtein-tyrosine kinase 5; Gtk; GTKEC 2.7.10.2; Nuclear tyrosine protein kinase RAK; PTK5 protein tyrosine kinase 5; PTK5; Rak; RAKPTK5; tyrosine-protein kinase FRK
Molecular Weight
Mass (kDA):
58.254 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q22.1 |
| Sequence: | 6; NC_000006.12 (115931149..116100739, complement) |
Tissue Specificity
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
Subcellular Localizations
Cytoplasm. Nucleus. Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Diseases
- Malignant Neoplasms
- Neoplasms
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Pheochromocytoma
- Malignant Neoplasm Of Prostate
- Cell Invasion
- Neoplasm Invasiveness
- Carcinoma
- Malignant Neoplasm Of Lung
Interacting Proteins
- BNIP2
- PTEN
- RB1
- SF3B4
Pathways
- Cell Differentiation
- Localization
- Pathogenesis
- Transport
- Fruit Development
- Cell Cycle
- Cell Proliferation
- Cell Death
- Secretion
- Glomerular Filtration
- Cell Growth
- Angiogenesis
- Cell Activation
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRK
bosterbio.com/bosterbio-gene-info-cards/FRK
References
PMID: 7696183 by Cance W.G., et al. Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.
PMID: 7510261 by Lee J., et al. Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase- encoding gene.