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FRMD5 Antibodies

AND FRMD5 ELISA kits, FRMD5 Proteins

Many biological assays use antibodies to detect FRMD5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRMD5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRMD5 antibodies...

We validate the specificity of these antibodies to FRMD5 by testing them on tissues known to express FRMD5 positively and negatively. Browse below to find the FRMD5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRMD5 Infographic by Boster Bio

FRMD5 protein infographic

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FRMD5 Overview

Facts about FERM domain-containing protein 5.

FRMD5 3D structure

FRMD5 3D structure. Source: alphafold

FERM domain-containing protein 5 (FRMD5)

May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions through its interaction with ITGB5 and changing ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1.

May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675). .

Gene Information

Human
Gene Name:	FRMD5
Uniprot:	Q7Z6J6
Entrez:	84978

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

FERM domain containing 5; FERM domain-containing protein 5; FLJ41022; MGC14161

Molecular Weight

Mass (kDA):
65.065 kDA

Molecular Weight

Genomic Context


Human

Location:	15q15.3
Sequence:	15; NC_000015.10 (43870764..44195271, complement)

Subcellular Localizations

Membrane; Single-pass membrane protein. Cell junction, adherens junction.

Subcellular Localization

Diseases

Neoplasms
Cell Invasion
Lung Neoplasms
Malignant Neoplasms
Tumor Progression
Glioblastoma
Neoplasm Invasiveness

Malignant Neoplasm Of Lung

Disease

Interacting Proteins

CTNND1
ITGB5
ROCK1

Interacting Proteins

Pathways

Cell Migration

Pathways

PTMs

Phosphoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRMD5

References

PMID: 22846708 by Wang T., et al. FERM-containing protein FRMD5 is a p120-catenin interacting protein that regulates tumor progression.

PMID: 25448675 by Hu J., et al. FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin beta5 subunit and ROCK1.