FRYL Antibodies

AND FRYL ELISA kits, FRYL Proteins

Many biological assays use antibodies to detect FRYL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRYL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRYL antibodies...

We validate the specificity of these antibodies to FRYL by testing them on tissues known to express FRYL positively and negatively. Browse below to find the FRYL antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRYL Infographic by Boster Bio

All FRYL Products

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Anti-FRYL Antibody Picoband®

Western blot analysis of FRYL using anti-FRYL antibody (A10865)

IHC analysis of FRYL using anti-FRYL antibody (A10865)

Human

ELISA, IHC, WB

$370
Cat # A10865
100 μg/vial

FRYL Overview

Facts about Protein furry homolog-like.

Protein furry homolog-like (FRYL)

Plays a crucial role in maintaining the integrity of polarized cell extensions during morphogenesis, modulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by restricting dendritic branching (By similarity). May function as a transcriptional activator.

Gene Information

Human
Gene Name:	FRYL
Uniprot:	O94915
Entrez:	285527

Family

Belongs to:

furry protein family

Alternative Names

AF4P12; ALL1-fused gene from chromosome 4p12 protein; DKFZp686E205; FLJ16177; FRY-like; furry homolog-like; furry-like; KIAA0826; protein furry homolog-like

Molecular Weight

Mass (kDA):
339.598 kDA

Genomic Context


Human

Location:	4p11
Sequence:	4; NC_000004.12 (48497357..48780323, complement)

Tissue Specificity

Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin.

Diseases

Leukemia
Neuroblastoma
Malignant Neoplasm Of Breast
Acute Lymphocytic Leukemia
Stage 4s Neuroblastoma
Carcinoma
Leukemia, Myelocytic, Acute
Dysplasia
Myeloid Leukemia
Therapy-related Acute Myeloid Leukemia
Chromosomal Translocation

Small Lymphocytic Lymphoma
Lymphoma
Cytogenetic Abnormality
Chronic Lymphocytic Leukemia
Dysmyelopoietic Syndromes

Interacting Proteins

DISC1

Pathways

Mating
Secretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRYL

References

PMID: 16061630 by Hayette S., et al. AF4p12, a human homologue to the furry gene of Drosophila, as a novel MLL fusion partner.

PMID: 21835304 by Ozgul R.K., et al. Exome sequencing and cis-regulatory mapping identify mutations in MAK, a gene encoding a regulator of ciliary length, as a cause of retinitis pigmentosa.