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- Table of Contents
Facts about Fibronectin type III and SPRY domain-containing protein 1.
| Human | |
|---|---|
| Gene Name: | FSD1 |
| Uniprot: | Q9BTV5 |
| Entrez: | 79187 |

| Belongs to: |
|---|
| No superfamily |

fibronectin type 3 and SPRY domain containing 1; fibronectin type III and SPRY domain containing 1; fibronectin type III and SPRY domain-containing protein 1; GLFNDfibronectin type 3 and SPRY (spla, ryanodine) domain containing (withcoiled-coil motif) 1; MGC3213; Microtubule-associated protein GLFND; midline 1-related protein 1; MIR1MID1-related protein 1
Mass (kDA):
55.82 kDA

| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (4304594..4323846) |
Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.





PMID: 11267680 by Carim-Todd L., et al. Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31.
PMID: 12445389 by Manabe R., et al. Identification of a novel microtubule-associated protein that regulates microtubule organization and cytokinesis by using a GFP- screening strategy.