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- Table of Contents
FANCA Antibodies
AND FANCA ELISA kits, FANCA Proteins
Many biological assays use antibodies to detect FANCA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCA antibodies...
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FANCA Infographic by Boster Bio
All FANCA Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03662-2
100 μg/vial
Cat # A03662-2
100 μg/vial
FANCA Overview
Facts about Fanconi anemia group A protein.
Fanconi anemia group A protein (FANCA)
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link fix and in the maintenance of normal chromosome stability.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FANCA |
| Uniprot: | O15360 |
| Entrez: | 2175 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FA; FA1; FAA; FAAMGC75158; FACA; FACAFanconi anemia group A protein; FAH; FA-H; FANCA; FANCH; Fanconi anemia, complementation group A; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA
Molecular Weight
Mass (kDA):
162.775 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q24.3 |
| Sequence: | 16; NC_000016.10 (89737549..89816647, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
Diseases
- Anemia
- Fanconi Anemia
- Malignant Neoplasms
- Pancytopenia
- Congenital Abnormality
- Neoplasms
- Hereditary Diseases
- Leukemia
- Malignant Neoplasm Of Breast
- Chromosome Breakage
- Myeloid Leukemia
- Leukemia, Myelocytic, Acute
- Aplastic Anemia
Interacting Proteins
- FAAP100
- FANCF
- FANCG
- GRB2
Pathways
- Hypersensitivity
- Dna Repair
- Localization
- Cell Cycle
- Pathogenesis
- Cell Death
- Chromosome Breakage
- Dna Replication
- Nuclear Import
- Senescence
- Nuclear Export
- Gene Conversion
- Interstrand Cross-link Repair
PTMs
- Phosphorylation
- Ubiquitination
- Methylation
Research Areas
- Cancer
- DNA Repair
- Genes Sensitive to DNA Damaging Agents
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FANCA
bosterbio.com/bosterbio-gene-info-cards/FANCA
References
PMID: 8896563 by Lo Ten Foe J.R., et al. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.
PMID: 9169126 by Ianzano L., et al. The genomic organization of the Fanconi anemia group A (FAA) gene.