Fbxl15 Antibodies

AND Fbxl15 ELISA kits, Fbxl15 Proteins

Many biological assays use antibodies to detect Fbxl15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fbxl15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fbxl15 antibodies...

We validate the specificity of these antibodies to Fbxl15 by testing them on tissues known to express Fbxl15 positively and negatively. Browse below to find the Fbxl15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Fbxl15 Infographic by Boster Bio

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Fbxl15 Overview

Facts about F-box/LRR-repeat protein 15.

F-box/LRR-repeat protein 15 (Fbxl15)

Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance.

Also mediates ubiquitination of SMURF2 and WWP2 (By similarity). .

Gene Information

Mouse
Gene Name:	Fbxl15
Uniprot:	Q91W61
Entrez:	68431

Family

Belongs to:

FBXL15 family

Alternative Names

F-box/LRR-repeat protein 15

Molecular Weight

Mass (kDA):
33.125 kDA

Genomic Context


Mouse

Location:	19\|19 C3
Sequence:	19;

Tissue Specificity

Expressed in heart, liver, spleen, bone, muscle, brain and kidney (at protein level).

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fbxl15

References

PMID: 21572392 by Cui Y., et al. SCF(FBXL15) regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.