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- Table of Contents
Facts about High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor.
Functions as a receptor for the Fc fragment of IgA and IgM.
Binds IgA and IgM with high affinity and mediates their endocytosis.May be the immune response to microbes mediated by IgA and IgM. .
| Mouse | |
|---|---|
| Gene Name: | Fcamr |
| Uniprot: | Q2TB54 |
| Entrez: | 64435 |

| Belongs to: |
|---|
| No superfamily |

CD351 antigen; CD351; Fc alpha/mu R; Fc alpha/mu receptor; Fc receptor, IgA, IgM, high affinity; FCA/MR; FCAMR; FKSG87; high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor; immunity related factor; receptor for Fc fragment of IgA and IgM; uR
Mass (kDA):
57.823 kDA

| Mouse | |
|---|---|
| Location: | 1|1 E4 |
| Sequence: | 1; |
Expressed in several tissues including thymus, spleen, liver, kidney, small and large intestine, testis and placenta. Expressed by oligodendrocytes, B-cells and macrophages but not granulocytes, T-cells or NK cells (at protein level).



PMID: 11062505 by Shibuya A., et al. Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes.
PMID: 11797105 by Shimizu Y., et al. Fc(alpha)/mu receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1.