GABRA3 Antibodies

AND GABRA3 ELISA kits, GABRA3 Proteins

Many biological assays use antibodies to detect GABRA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRA3 antibodies...

We validate the specificity of these antibodies to GABRA3 by testing them on tissues known to express GABRA3 positively and negatively. Browse below to find the GABRA3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GABRA3 Infographic by Boster Bio

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GABRA3 Overview

Facts about Gamma-aminobutyric acid receptor subunit alpha-3.

GABRA3 3D structure. Source: alphafold

Gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3)

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. .

Gene Information

Human
Gene Name:	GABRA3
Uniprot:	P34903
Entrez:	2556

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

GABA A R alpha 3; GABA(A) receptor subunit alpha-3; GABAARa3; GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3; gamma-aminobutyric acid receptor subunit alpha-3; gamma-animobutyric acid (GABA) A receptor, alpha 3; MGC33793

Molecular Weight

Mass (kDA):
55.165 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (152166234..152451341, complement)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Anxiety Disorders
Bipolar Disorder
Epilepsy
Depressive Disorder
Nervousness
Ataxia
Dysequilibrium Syndrome
Schizophrenia
Absence Epilepsy
Mood Disorders
Nervous System Disorder
Stress, Psychological

Rett Syndrome
Sex Chromosome Aberrations
Mental Disorders
Color Vision Defect
Steroid Sulfatase Deficiency Disease
Tissue Adhesions
Migraine Disorders

Pathways

Brain Development
Localization
Synaptic Transmission
Coagulation
Pathogenesis
Cell Adhesion
Blood Coagulation
Developmental Process
Prepulse Inhibition
Signal Transmission
Aging
Immune Response

Pigmentation
Reflex
Swimming
Cell Cycle
Cell Growth
Mating

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRA3

References

PMID: 10602120 by Amir R., et al. Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq.

PMID: 26613940 by Dejanovic B., et al. Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.