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- Table of Contents
GABRG2 Antibodies
AND GABRG2 ELISA kits, GABRG2 Proteins
Many biological assays use antibodies to detect GABRG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRG2 antibodies...
Designing a Western blot for GABRG2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GABRG2 Western Blot GuideGABRG2 Infographic by Boster Bio
All GABRG2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02361-1
100 μg/vial
Cat # A02361-1
100 μg/vial
Human
$628
Cat # LS002566
20 µg, 100 µg
Cat # LS002566
20 µg, 100 µg
GABRG2 Overview
Facts about Gamma-aminobutyric acid receptor subunit gamma-2.
Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2)
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine.
Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.
Gene Information
| Human | |
|---|---|
| Gene Name: | GABRG2 |
| Uniprot: | P18507 |
| Entrez: | 2566 |
Family
| Belongs to: |
|---|
| ligand-gated ion channel (TC 1.A.9) family |
Alternative Names
CAE2; ECA2; GABA A R gamma 2; GABA(A) receptor subunit gamma-2; GABAAR gamma 2; GABAARg2; GABRG2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid receptor subunit gamma-2; GEFSP3
Molecular Weight
Mass (kDA):
54.162 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q34 |
| Sequence: | 5; NC_000005.10 (162067465..162155539) |
Subcellular Localizations
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cytoplasmic vesicle membrane.
Diseases
- Epilepsy
- Febrile Convulsions
- Epilepsy, Generalized
- Absence Epilepsy
- Epilepsies, Myoclonic
- Infantile Severe Myoclonic Epilepsy
- Nervousness
- Dysequilibrium Syndrome
- Convulsions
- Nervous System Disorder
- Schizophrenia
- Anxiety Disorders
Interacting Proteins
- GABARAP
- NOVA1
Pathways
- Pathogenesis
- Localization
- Translation
- Synaptic Transmission
- Endocytosis
- Glycosylation
- Drug Resistance
- Synapse Maturation
- Transport
- Gephyrin Clustering
- Reflex
- Mrna Splicing
- Swimming
PTMs
- Phosphorylation
Research Areas
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRG2
bosterbio.com/bosterbio-gene-info-cards/GABRG2
References
PMID: 2538761 by Pritchett D.B., et al. Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology.
PMID: 11328646 by Jiang S., et al. Complete genomic sequence of 195 Kb of human DNA containing the gene GABRG2.