GAMT Antibodies

AND GAMT ELISA kits, GAMT Proteins

Many biological assays use antibodies to detect GAMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GAMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GAMT antibodies...

We validate the specificity of these antibodies to GAMT by testing them on tissues known to express GAMT positively and negatively. Browse below to find the GAMT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GAMT Infographic by Boster Bio

All GAMT Products

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Figures

Specificity

Applications

Price

Anti-GAMT Antibody

Western blot analysis of extracts of various cell lines, using GAMT antibody at 1:1000 dilution

Immunofluorescence analysis of A549 cells using GAMT Rabbit pAb at dilution of 1:200

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02886
100ul

GAMT (NM_000156) Human Recombinant Protein

Coomassie blue staining of purified GAMT protein

$1249
Cat # PROTQ14353
20 µg

Anti-GAMT Antibody Picoband®

Western blot analysis of GAMT using anti-GAMT antibody (A02886-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02886-2
100 µg/vial

GAMT Overview

Facts about Guanidinoacetate N-methyltransferase.

GAMT 3D structure. Source: alphafold

Guanidinoacetate N-methyltransferase (GAMT)

Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor (PubMed:26003046, PubMed:24415674, PubMed:26319512). Significant in nervous system development (PubMed:24415674).

Gene Information

Human
Gene Name:	GAMT
Uniprot:	Q14353
Entrez:	2593

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

EC 2.1.1.2; guanidinoacetate N-methyltransferase; PIG2; TP53I2

Molecular Weight

Mass (kDA):
26.318 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (1397026..1401542, complement)

Tissue Specificity

Expressed in liver.

Diseases

Epilepsy
Inborn Errors Of Metabolism
Deficiency Of Guanidinoacetate Methyltransferase
Movement Disorders
Brain Diseases, Metabolic, Inborn
Developmental Delay (disorder)
Muscle Hypotonia
Language Delays
Nervousness
Autistic Disorder
Autistic Behavior

Deficiency Diseases
Metabolic Diseases
Globus Hystericus
Speech Delay
Malnutrition
Extrapyramidal Sign

Pathways

Transport
Creatine Transport
Methylation
Proteolysis
Energy Homeostasis
Excretion
Oxidative Phosphorylation
Reverse Transcription
Transsulfuration
Localization
Regeneration
Pathogenesis
Fatty Acid Oxidation

Glycolysis
Secretion
Brain Development
Cell Cycle
Cognition
Segmentation
Response To Nutrient

PTMs

Phosphorylation
Methylation
Reduction

Oxidation
Carboxylation
Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAMT

References

PMID: 8547310 by Isbrandt D., et al. Cloning and sequence analysis of human guanidinoacetate N- methyltransferase cDNA.

PMID: 9325156 by Jenne D.E., et al. The human guanidinoacetate methyltransferase (GAMT) gene maps to a syntenic region on 19p13.3, homologous to band C of mouse chromosome 10, but GAMT is not mutated in jittery mice.