GAS2 Antibodies

AND GAS2 ELISA kits, GAS2 Proteins

Many biological assays use antibodies to detect GAS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GAS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GAS2 antibodies...

We validate the specificity of these antibodies to GAS2 by testing them on tissues known to express GAS2 positively and negatively. Browse below to find the GAS2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GAS2 Infographic by Boster Bio

All GAS2 Products

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Figures

Specificity

Applications

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Anti-GAS2 Antibody

Western blot analysis of extracts of various cell lines, using GAS2 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human liver cancer using GAS2 antibody at dilution of 1:200

Human, Mouse

IHC, WB

$405
Cat # A08589
100ul

GAS2 (NM_005256) Human Recombinant Protein

Coomassie blue staining of purified GAS2 protein

$1249
Cat # PROTO43903
20 µg

Anti-GAS2 Antibody Picoband®

Western blot analysis of GAS2 using anti-GAS2 antibody (A08589-1)

Flow Cytometry analysis of Jurkat cells using anti-GAS2 antibody (A08589-1)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A08589-1
100 μg/vial

GAS2 (NM_005256) Human Over-expression Lysate

GAS2 Human Over-expression Lysates NM_001143830

Human

$628
Cat # LS002620
20 µg, 100 µg

Anti-GAS2 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Western blot analysis of GAS2 expression in Jurkat cell lysate

Human

IHC, WB

$370
Cat # M08589
100 µl/vial

GAS2 Overview

Facts about Growth arrest-specific protein 2.

GAS2 3D structure. Source: alphafold

Growth arrest-specific protein 2 (GAS2)

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells.

May be involved in the membrane ruffling procedure (By similarity). .

Gene Information

Human
Gene Name:	GAS2
Uniprot:	O43903
Entrez:	2620

Family

Belongs to:

GAS2 family

Alternative Names

GAS-2; growth arrest-specific 2; growth arrest-specific protein 2; MGC32610

Molecular Weight

Mass (kDA):
34.945 kDA

Genomic Context


Human

Location:	11p14.3
Sequence:	11; NC_000011.10 (22627758..22885930)

Tissue Specificity

Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.

Subcellular Localizations

Cytoplasm, cytoskeleton, stress fiber. Membrane; Peripheral membrane protein. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

Diseases

Growth Arrest
Malignant Neoplasms
Cell Transformation, Neoplastic
Neoplasms
Mammary Neoplasms
Tissue Adhesions
Myeloid Leukemia, Chronic
Myeloid Leukemia
Prostatic Neoplasms
Nervousness
Infective Disorder
Malignant Neoplasm Of Prostate

Blast Phase
Retinoblastoma
Leukemia
Embryonal Carcinoma
Malignant Neoplasm Of Breast
Malignant Tumor Of Colon

Pathways

Cell Cycle
Cell Death
Cell Wall Assembly
Spore Wall Assembly
Germination
Virulence
Sporulation
Cell Growth
Cell Adhesion
Cell Division
Oncogenesis
Pathogenesis
Gene Silencing

Muscle Attachment
Senescence
Apoptotic Process
Dna Demethylation
Nuclear Export
Chondrocyte Proliferation
Cytokinesis

PTMs

Cleavage
Phosphorylation

Glycosylation
Methylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAS2

References

PMID: 9521882 by Collavin L., et al. cDNA characterization and chromosome mapping of the human GAS2 gene.

PMID: 24706950 by Stroud M.J., et al. GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.