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May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the possible function of the enzymatically inactive isoforms remains unknown.
|GTP cyclohydrolase I family|
|Sequence:||14; NC_000014.9 (54842005..54902826, complement)|
In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).