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- Table of Contents
GCLC Antibodies
AND GCLC ELISA kits, GCLC Proteins
Many biological assays use antibodies to detect GCLC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCLC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCLC antibodies...
Designing a Western blot for GCLC? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GCLC Western Blot GuideDesigning an IHC experiment for GCLC? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GCLC IHC GuideGCLC Infographic by Boster Bio
All GCLC Products
Product
Figures
Specificity
Applications
Price
Anti-GCLC Antibody Picoband®
3 Citations
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PB9201
100 μg/vial
Cat # PB9201
100 μg/vial
Anti-GCLC Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01722
100 μg/vial
Cat # A01722
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M01722-2
20μL, 40μL, 100μL, 200μL
Cat # M01722-2
20μL, 40μL, 100μL, 200μL
GCLC Overview
Facts about Glutamate--cysteine ligase catalytic subunit.
Glutamate--cysteine ligase catalytic subunit (GCLC)
Gene Information
| Human | |
|---|---|
| Gene Name: | GCLC |
| Uniprot: | P48506 |
| Entrez: | 2729 |
Family
| Belongs to: |
|---|
| glutamate--cysteine ligase type 3 family |
Alternative Names
EC 6.3.2.2; gamma-ECS; Gamma-glutamylcysteine synthetase; GCS heavy chain; GCS; GLCL; GLCLCGCL; glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit
Molecular Weight
Mass (kDA):
72.766 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p12.1 |
| Sequence: | 6; NC_000006.12 (53497341..53545101, complement) |
Diseases
- Malignant Neoplasms
- Liver Carcinoma
- Hepatotoxicity
- Liver Diseases
- Inflammation
- Injury To Liver
- Neoplasms
- Diabetes Mellitus
- Infarction
- Lung Diseases
- Steatohepatitis
- Adenocarcinoma
Pathways
- Cell Death
- Pathogenesis
- Response To Oxidative Stress
- Cell Proliferation
- Aging
- Conjugation
- Inflammatory Response
- Cell Cycle
- Localization
- Transport
- Translation
- Neuroprotection
- Cellular Homeostasis
PTMs
- Phosphorylation
- Reduction
- Oxidation
- Cleavage
Research Areas
- Cell Biology
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCLC
bosterbio.com/bosterbio-gene-info-cards/GCLC
References
PMID: 1350904 by Gipp J.J., et al. Cloning and nucleotide sequence of a full-length cDNA for human liver gamma-glutamylcysteine synthetase.
PMID: 7726839 by Mulcahy R.T., et al. Identification of a putative antioxidant response element in the 5'- flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene.
4 Publications of Boster GCLC Antibodies & ELISA Kits
- PubMed ID: 10.1155/2021/6688708, Fucoxanthin Prevents 6-OHDA-Induced Neurotoxicity by Targeting Keap1
- PubMed ID: -, Zhilei Mao,Shushu Li,Lina Zhang,Mengmeng Yao,Zhu Zhou,Minjian Chen,"The mTOR/GCL...
- PubMed ID: 27630691, Electroacupuncture alleviates cerebral ischemia and reperfusion injury via modul...
- PubMed ID: 26339340, Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary f...
*More publications can be found for each product on its corresponding product page