GDF3 Antibodies

AND GDF3 ELISA kits, GDF3 Proteins

Many biological assays use antibodies to detect GDF3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDF3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDF3 antibodies...

We validate the specificity of these antibodies to GDF3 by testing them on tissues known to express GDF3 positively and negatively. Browse below to find the GDF3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GDF3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GDF3 Western Blot Guide

GDF3 Infographic by Boster Bio

All GDF3 Products

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Product

Figures

Specificity

Applications

Price

Anti-GDF3 Rabbit Monoclonal Antibody

Western blot analysis of GDF3 expression in 293T cell lysate

Human, Mouse, Rat

$370
Cat # M06869
100 μl/vial

Anti-GDF-3 Antibody

Western Blot (WB) analysis of L929 cells using GDF-3 Polyclonal antibody

Western Blot (WB) analysis of K562 KB using GDF-3 Polyclonal antibody diluted at 1:500

Human, Mouse

ELISA, WB

$399
Cat # A06869
100μl

GDF3 (NM_020634) Human Over-expression Lysate

Human

$628
Cat # LS009573
20 µg, 100 µg

GDF3 Overview

Facts about Growth/differentiation factor 3.

GDF3 3D structure. Source: alphafold

Growth/differentiation factor 3 (GDF3)

Growth factor involved in early embryonic development and adipose-tissue homeostasis. Throughout embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity).

Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089). .

Gene Information

Human
Gene Name:	GDF3
Uniprot:	Q9NR23
Entrez:	9573

Family

Belongs to:

TGF-beta family

Alternative Names

GDF3; GDF-3; growth differentiation factor 3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6; Vgr-2

Molecular Weight

Mass (kDA):
41.387 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (7689784..7695775, complement)

Subcellular Localizations

Secreted. Cytoplasm. Mainly accumulated in the cytoplasm.

Diseases

Neoplasms
Carcinoma
Teratoma
Germ Cell Tumor
Testicular Neoplasms
Embryonal Carcinoma
Cell Transformation, Neoplastic
Seminoma
Idiopathic Hypereosinophilic Syndrome
Testicular Germ Cell Tumor
Obesity
Malignant Neoplasms
Malignant Neoplasm Of Breast

Neoplasms, Germ Cell And Embryonal
Teratocarcinoma
Infertility
Endometriosis, Site Unspecified
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Diabetes Mellitus

Pathways

Cell Differentiation
Methylation
Cell Growth
Secretion
Reverse Transcription
Gastrulation
Regeneration
Pathogenesis
Cell Adhesion
Colony Morphology
Stem Cell Differentiation
Fertilization
Nodal Signaling Pathway

Mesoderm Formation
Regulation Of Gene Expression
Cell Cycle Arrest
Glucose Homeostasis
Cell Cycle
Segmentation
Oncogenesis

PTMs

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDF3

References

PMID: 21805089 by Li Q., et al. The conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cells.

PMID: 19864492 by Ye M., et al. Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies.