GDI1 Antibodies

AND GDI1 ELISA kits, GDI1 Proteins

Many biological assays use antibodies to detect GDI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDI1 antibodies...

We validate the specificity of these antibodies to GDI1 by testing them on tissues known to express GDI1 positively and negatively. Browse below to find the GDI1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: GDI2

GDI1 Infographic by Boster Bio

All GDI1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human GDI1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP31150
Starting from 10ug

Anti-GDI1 Mouse Monoclonal Antibody [Clone ID: OTI1B1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GDI1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 3 cell lines by using anti-GDI1 monoclonal antibody (1:500)

Immunohistochemical staining of paraffin-embedded Human embryonic cerebellum within the normal limits using anti-GDI1 mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M04179
100 µl

GDI1 (NM_001493) Human Over-expression Lysate

Human

$628
Cat # LS002664
20 µg, 100 µg

Anti-GDI1 Antibody Picoband®

Western blot analysis of GDI1 using anti-GDI1 antibody (A04179-2)

IHC analysis of GDI1 using anti-GDI1 antibody (A04179-2)

Immunoprecipitating GDI1 in SH-SY5Y whole cell lysate

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A04179-2
100 μg/vial

GDI1 Overview

Facts about Rab GDP dissociation inhibitor alpha.

GDI1 3D structure. Source: alphafold

Rab GDP dissociation inhibitor alpha (GDI1)

Regulates the GDP/GTP exchange response of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation.

Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. .

Gene Information

Human
Gene Name:	GDI1
Uniprot:	P31150
Entrez:	2664

Family

Belongs to:

Rab GDI family

Alternative Names

FLJ41411; GDI-1; GDIL; GDP dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 41; mental retardation, X-linked 48; MRX41; oligophrenin-2; OPHN2MRX48; Protein XAP-4; Rab GDI alpha; rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGDIARABGD1A; XAP4; XAP-4

Molecular Weight

Mass (kDA):
50.583 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (154437154..154443467)

Tissue Specificity

Brain; predominant in neural and sensory tissues.

Subcellular Localizations

Cytoplasm. Golgi apparatus, trans-Golgi network.

Diseases

Nervousness
Malnutrition
Fragile X Syndrome
Impaired Cognition
Memory Impairment
Learning Disorders
Glioma
Single Gene Defect
Hemophilia A
Chromosome Breakage
Legionnaires' Disease

Hereditary Diseases
Muscle Degeneration
Rett Syndrome
Genetic Diseases, X-linked
Nervous System Disorder

Interacting Proteins

LNX1
Rab10
RAB1A
RAB4A

Pathways

Transport
Secretory Pathway
Vesicle Transport
Vesicle Fusion
Localization
Short-term Memory
Long-term Synaptic Potentiation
Regulation Of Rho Gtpase Activity
Regulation Of Signal Transduction
Pinocytosis
Synaptic Vesicle Transport
Protein Transport
Cytokinesis

Cytoskeleton Organization
Translation
Phagocytosis
Synaptic Vesicle Fusion
Conditioned Taste Aversion
Social Behavior
Cognition

PTMs

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDI1

References

PMID: 7849400 by Sedlacek Z., et al. Evolutionary conservation and genomic organization of XAP-4, an Xq28 located gene coding for a human rab GDP-dissociation inhibitor (GDI).

PMID: 7585614 by Nishimura N., et al. Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.