GGT2 Antibodies

AND GGT2 ELISA kits, GGT2 Proteins

Many biological assays use antibodies to detect GGT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GGT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GGT2 antibodies...

We validate the specificity of these antibodies to GGT2 by testing them on tissues known to express GGT2 positively and negatively. Browse below to find the GGT2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GGT2 Infographic by Boster Bio

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GGT2 Overview

Facts about Inactive glutathione hydrolase 2.

GGT2 3D structure. Source: alphafold

Inactive glutathione hydrolase 2 (GGT2)

Isoform 1, isoform 2 and isoform 3 lack catalytic activity due to its inability to experience the autocatalytic cleavage needed to generate a mature, enzymatically active heterodimer. .

Gene Information

Human
Gene Name:	GGT2
Uniprot:	P36268
Entrez:	728441

Family

Belongs to:

gamma-glutamyltransferase family

Alternative Names

gamma-glutamyltransferase 2; gamma-glutamyltranspeptidase 2

Molecular Weight

Mass (kDA):
61.771 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (21207972..21283023, complement)

Tissue Specificity

Highly expressed in fetal and adult kidney and liver.

Subcellular Localizations

Cytoplasm, perinuclear region. Endoplasmic reticulum. Co-localizes with calnexin in the endoplasmic reticulum.

Diseases

Liver Diseases
Digeorge Syndrome
Cell Transformation, Neoplastic
Malignant Neoplasms
Conotruncal Heart Malformations (disorder)
Liver Carcinoma
Hepatitis

Chromosome Breakage

Pathways

Localization
Senescence
Protein Prenylation
Reverse Transcription
Cell Growth
Prenylation
Meiosis
Rna Interference

Conjugation
Secretion

PTMs

Cleavage

Methylation

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GGT2

References

PMID: 2573352 by Pawlak A., et al. Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.

PMID: 23682772 by West M.B., et al. Human GGT2 does not autocleave into a functional enzyme: a cautionary tale for interpretation of microarray data on redox signaling.