GMDS Antibodies

AND GMDS ELISA kits, GMDS Proteins

Many biological assays use antibodies to detect GMDS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMDS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMDS antibodies...

We validate the specificity of these antibodies to GMDS by testing them on tissues known to express GMDS positively and negatively. Browse below to find the GMDS antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GMDS Infographic by Boster Bio

All GMDS Products

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Product

Figures

Specificity

Applications

Price

Anti-GDP-mannose 4,6 dehydratase GMDS Antibody

Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night

Human, Mouse

ELISA, WB

$380
Cat # A05783
100ul

GMDS (NM_001500) Human Recombinant Protein

Coomassie blue staining of purified GMDS protein

$1249
Cat # PROTO60547
20 µg

Anti-GMDS Mouse Monoclonal Antibody [Clone ID: OTI2A1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from a mouse tissue by using anti-GMDS monoclonal antibody (1:200)

Human, Mouse, Rat

$523
Cat # M05783
100 µl

GMDS (NM_001500) Human Over-expression Lysate

Human

$628
Cat # LS002762
20 µg, 100 µg

Anti-GMDS Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A05783-1
100 μl/vial

GMDS Overview

Facts about GDP-mannose 4,6 dehydratase.

GMDS 3D structure. Source: alphafold

GDP-mannose 4,6 dehydratase (GMDS)

Catalyzes the conversion of GDP-D-mannose into GDP-4- dehydro-6-deoxy-D-mannose.
.

Gene Information

Human
Gene Name:	GMDS
Uniprot:	O60547
Entrez:	2762

Family

Belongs to:

NAD(P)-dependent epimerase/dehydratase family

Alternative Names

EC 4.2.1.47; GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase; GMDGDP-mannose 4,6 dehydratase; SDR3E1; short chain dehydrogenase/reductase family 3E, member 1

Molecular Weight

Mass (kDA):
41.95 kDA

Genomic Context


Human

Location:	6p25.3
Sequence:	6; NC_000006.12 (1623800..2245605, complement)

Diseases

Neoplasm Metastasis
Malignant Neoplasms
Malignant Tumor Of Colon
Small For Gestational Age (disorder)
Depressive Disorder
Colonic Neoplasms
Carcinogenesis
Developmental Delay (disorder)
Developmental Disabilities
Metaplasia
Pregnancy Complications
Neoplasms, Glandular And Epithelial

Immunologic Deficiency Syndromes
Dysplasia
Neoplasms
Headache
Ovarian Neoplasm
Esophageal Neoplasms

Interacting Proteins

WDYHV1

Pathways

Fucosylation
Glycosylation
Methylation
Drug Resistance
Swimming
Translation
Habituation
Dna Methylation

Pathogenesis
Demethylation

PTMs

Acetylation

Phosphoprotein

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMDS

References

PMID: 9525924 by Sullivan F.X., et al. Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro.

PMID: 9603974 by Ohyama C., et al. Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells.