GMPPA Antibodies

AND GMPPA ELISA kits, GMPPA Proteins

Many biological assays use antibodies to detect GMPPA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMPPA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMPPA antibodies...

We validate the specificity of these antibodies to GMPPA by testing them on tissues known to express GMPPA positively and negatively. Browse below to find the GMPPA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GMPPA Infographic by Boster Bio

All GMPPA Products

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Product

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Specificity

Applications

Price

GMPPA (NM_013335) Human Over-expression Lysate

Human

$628
Cat # LS029926
20 µg, 100 µg

Anti-GMPPA Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A13702-1
100 μl/vial

GMPPA Overview

Facts about Mannose-1-phosphate guanyltransferase alpha.

Mannose-1-phosphate guanyltransferase alpha (GMPPA)

May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. .

Gene Information

Human
Gene Name:	GMPPA
Uniprot:	Q96IJ6
Entrez:	29926

Family

Belongs to:

transferase hexapeptide repeat family

Alternative Names

EC 2.7.7; EC 2.7.7.13; GDP-mannose pyrophosphorylase Amannose-1-phosphate guanyltransferase alpha; GTP-mannose-1-phosphate guanylyltransferase alpha; mannose-1-phosphate guanylyltransferase (GDP)

Molecular Weight

Mass (kDA):
46.291 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (219498891..219506989)

Tissue Specificity

Expressed in fibroblasts (at protein level).

Subcellular Localizations

Cytoplasm. Myc-tagged GMPPA shows a diffuse cytoplasmic and nuclear pattern in transfected COS-7 cells.

Diseases

Alacrima, achalasia, and mental retardation syndrome (AAMR)

Interacting Proteins

BTC
CRP
GMPPB

Pathways

Senescence
Methylation
Dna Replication
Cell Cycle
Dna Methylation

PTMs

Methylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMPPA

References

PMID: 24035193 by Koehler K., et al. Mutations in GMPPA cause a glycosylation disorder characterized by intellectual disability and autonomic dysfunction.