GMP reductase 1 Antibodies

AND GMPR ELISA kits, GMP reductase 1 Proteins

Many biological assays use antibodies to detect GMP reductase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMP reductase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMP reductase 1 antibodies...

We validate the specificity of these antibodies to GMP reductase 1 by testing them on tissues known to express GMPR positively and negatively. Browse below to find the GMPR antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GMPR Infographic by Boster Bio

All GMPR Products

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GMPR1 (GMPR) (NM_006877) Human Recombinant Protein

Coomassie blue staining of purified GMPR protein

$1249
Cat # PROTP36959
20 µg

Anti-GMPR1 (GMPR) Mouse Monoclonal Antibody [Clone ID: OTI1E8]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMPR (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M09309
100 µl

GMPR1 (GMPR) (NM_006877) Human Over-expression Lysate

Human

$628
Cat # LS002766
20 µg, 100 µg

Anti-GMPR Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # A09309
100 μl/vial

GMPR Overview

Facts about GMP reductase 1.

GMPR 3D structure. Source: alphafold

GMP reductase 1 (GMPR)

Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.
It works in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

Gene Information

Human
Gene Name:	GMPR
Uniprot:	P36959
Entrez:	2766

Family

Belongs to:

IMPDH/GMPR family

Alternative Names

EC 1.7.1.7; GMPR1GMP reductase 1; guanine monophosphate reductase; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1; guanosine monophosphate reductase

Molecular Weight

Mass (kDA):
37.419 kDA

Genomic Context


Human

Location:	6p22.3
Sequence:	6; NC_000006.12 (16238587..16295549)

Diseases

Leukemia
Coronary Artery Disease
Coronary Heart Disease
Ischemia
Ataxia
Schizophrenia
Pathological Dilatation
Leukemia, Myelocytic, Acute
Cardiovascular Diseases
Metabolic Diseases
Malignant Neoplasms

Myeloid Leukemia
Acute Promyelocytic Leukemia
Ataxia, Spinocerebellar
Ventricular Dysfunction
Opca, Menzel Type

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMPR

References

PMID: 2758468 by Kanno H., et al. Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase.

PMID: 1661705 by Kondoh T., et al. Genomic structure and expression of human guanosine monophosphate reductase.