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- Table of Contents
GNA11 Antibodies
AND GNA11 ELISA kits, GNA11 Proteins
Many biological assays use antibodies to detect GNA11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNA11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNA11 antibodies...
Designing an IHC experiment for GNA11? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GNA11 IHC GuideGNA11 Infographic by Boster Bio
All GNA11 Products
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GNA11 Overview
Facts about Guanine nucleotide-binding protein subunit alpha-11.
Guanine nucleotide-binding protein subunit alpha-11 (GNA11)
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
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Gene Information
| Human | |
|---|---|
| Gene Name: | GNA11 |
| Uniprot: | P29992 |
| Entrez: | 2767 |
Family
| Belongs to: |
|---|
| G-alpha family |
Alternative Names
G alpha-11; GA11; GNA-11; G-protein subunit alpha-11; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); Guanine nucleotide-binding protein G(y) subunit alpha; guanine nucleotide-binding protein subunit alpha-11; guanine nucleotide-binding protein, Gq class, GNA11
Molecular Weight
Mass (kDA):
42.123 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (3094362..3123999) |
Tissue Specificity
Expressed in testis.
Subcellular Localizations
Cell membrane; Lipid-anchor. Cytoplasm. In testicular cells, expressed exclusively in the cytoplasm.
Diseases
- Melanoma
- Neoplasms
- Uveal Melanoma
- Uveal Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Melanocytic Nevus
- Malignant Paraganglionic Neoplasm
- Nevus, Blue
- Skin Neoplasms
- Metastatic Malignant Neoplasm To The Liver
- Malignant Neoplasm Of Breast
Pathways
- Cell Cycle
- Cell Cycle Arrest
- Methylation
- Pathogenesis
- Enucleation
- Cell Proliferation
- Induction Of Apoptosis
- Mitosis
- Pigmentation
- Eating Behavior
- Response To Paclitaxel
- Localization
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNA11
bosterbio.com/bosterbio-gene-info-cards/GNA11
References
PMID: 1902575 by Jiang M., et al. Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells.
PMID: 7492305 by Thomas C.P., et al. Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.