GNAL Antibodies

AND GNAL ELISA kits, GNAL Proteins

Many biological assays use antibodies to detect GNAL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNAL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNAL antibodies...

We validate the specificity of these antibodies to GNAL by testing them on tissues known to express GNAL positively and negatively. Browse below to find the GNAL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for GNAL? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GNAL IHC Guide

GNAL Infographic by Boster Bio

All GNAL Products

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Specificity

Applications

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Anti-GNAL Antibody Picoband®

Western blot analysis of GNAL using anti-GNAL antibody (A09404-1)

IHC analysis of GNAL using anti-GNAL antibody (A09404-1)

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A09404-1
100 μg/vial

GNAL (NM_182978) Human Over-expression Lysate

GNAL Human Over-expression Lysates NM_001142339

Human

$628
Cat # LS002774
20 µg, 100 µg

GNAL Overview

Facts about Guanine nucleotide-binding protein G(olf) subunit alpha.

GNAL 3D structure. Source: alphafold

Guanine nucleotide-binding protein G(olf) subunit alpha (GNAL)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia.

May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters. .

Gene Information

Human
Gene Name:	GNAL
Uniprot:	P38405
Entrez:	2774

Family

Belongs to:

G-alpha family

Alternative Names

Adenylate cyclase-stimulating G alpha protein, olfactory type; guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory typ; guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory type; guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide, olfactory type; guanine nucleotide-binding protein G(olf) subunit alpha

Molecular Weight

Mass (kDA):
44.308 kDA

Genomic Context


Human

Location:	18p11.21
Sequence:	18; NC_000018.10 (11689015..11885685)

Tissue Specificity

Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.

Diseases

Mood Disorders
Bipolar Disorder
Schizophrenia
Attention Deficit Hyperactivity Disorder
Dystonia Disorders
Malnutrition
Trinucleotide Repeat Expansion
Hypoxia
Myeloid Leukemia, Chronic
Coronary Artery Disease
Parkinson Disease
Organic Writer's Cramp

Fibrosis
Dyskinetic Syndrome
Malignant Neoplasms
Inattention
Dyskinesia, Drug-induced
Mammary Neoplasms
Dysequilibrium Syndrome

Pathways

Bioluminescence
Reverse Transcription
Circadian Rhythm
Cell Cycle
Cell Death
Photosynthesis

Sarcomere Organization

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNAL

References

PMID: 8243272 by Zigman J.M., et al. Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.

PMID: 23994616 by Wu Y.C., et al. A novel Galphas-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.