GNB1 Antibodies

AND GNB1 ELISA kits, GNB1 Proteins

Many biological assays use antibodies to detect GNB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNB1 antibodies...

We validate the specificity of these antibodies to GNB1 by testing them on tissues known to express GNB1 positively and negatively. Browse below to find the GNB1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: GNB2

GNB1 Infographic by Boster Bio

All GNB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GNB1 Antibody Picoband®

3 Q&As

Western blot analysis of GNB1 using anti-GNB1 antibody (PB10067)

IHC analysis of GNB1 using anti-GNB1 antibody (PB10067)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # PB10067
100 μg/vial

Human GNB1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$265
Cat # PROTP62873
Starting from 10ug

Anti-GNB1 Antibody Picoband® (monoclonal, 11F9)

Western blot analysis of GNB1 using anti-GNB1 antibody (M04650)

IF analysis of GNB1 using anti-GNB1 antibody (M04650)

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M04650
100 μg/vial

GNB1 (NM_002074) Human Over-expression Lysate

Human

$628
Cat # LS002782
20 µg, 100 µg

GNB1 Overview

Facts about Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.

GNB1 3D structure. Source: alphafold

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1)

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.

Gene Information

Human
Gene Name:	GNB1
Uniprot:	P62873
Entrez:	2782

Family

Belongs to:

WD repeat G protein beta family

Alternative Names

beta subunit, signal-transducing proteins GS/GI; G protein, beta-1 subunit; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1

Molecular Weight

Mass (kDA):
37.377 kDA

Genomic Context


Human

Location:	1p36.33
Sequence:	1; NC_000001.11 (1785285..1891117, complement)

Diseases

Neuroblastoma
Retinal Degeneration
Malignant Neoplasms
Retinitis Pigmentosa
Amaurosis
Hepatitis, Chronic
Infarction
Melanoma
Degenerative Disorder
Substance-related Disorders
Hepatitis C, Chronic
Endometrial Neoplasms

Endometrial Polyp
Sarcoma
Carcinoma
Myocardial Infarction
Neoplasms
Chromosome Breakage

Interacting Proteins

GNG2
NCF2

Pathways

Cell Proliferation
Sensitization
Neural Tube Closure
Cell Migration
Regulation Of Growth
Neurogenesis
Localization
Ion Homeostasis
Methylation
Tube Closure
Reverse Transcription
Axon Guidance
Cell Death

Cell Cycle
Regulation Of Cell Migration
Cell Growth
Phototransduction
Estrus
Metal Ion Homeostasis
Pathogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNB1

References

PMID: 3095147 by Codina J., et al. Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical.

PMID: 14512443 by Niu J., et al. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.