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- Table of Contents
GNB1 Antibodies
AND GNB1 ELISA kits, GNB1 Proteins
Many biological assays use antibodies to detect GNB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNB1 antibodies...
Designing a Western blot for GNB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GNB1 Western Blot GuideGNB1 Infographic by Boster Bio
All GNB1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB10067
100 μg/vial
Cat # PB10067
100 μg/vial
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # M04650
100 μg/vial
Cat # M04650
100 μg/vial
GNB1 Overview
Facts about Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1)
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Gene Information
| Human | |
|---|---|
| Gene Name: | GNB1 |
| Uniprot: | P62873 |
| Entrez: | 2782 |
Family
| Belongs to: |
|---|
| WD repeat G protein beta family |
Alternative Names
beta subunit, signal-transducing proteins GS/GI; G protein, beta-1 subunit; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1
Molecular Weight
Mass (kDA):
37.377 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.33 |
| Sequence: | 1; NC_000001.11 (1785285..1891117, complement) |
Diseases
- Neuroblastoma
- Retinal Degeneration
- Malignant Neoplasms
- Retinitis Pigmentosa
- Amaurosis
- Hepatitis, Chronic
- Infarction
- Melanoma
- Degenerative Disorder
- Substance-related Disorders
- Hepatitis C, Chronic
- Endometrial Neoplasms
Interacting Proteins
- GNG2
- NCF2
Pathways
- Cell Proliferation
- Sensitization
- Neural Tube Closure
- Cell Migration
- Regulation Of Growth
- Neurogenesis
- Localization
- Ion Homeostasis
- Methylation
- Tube Closure
- Reverse Transcription
- Axon Guidance
- Cell Death
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNB1
bosterbio.com/bosterbio-gene-info-cards/GNB1
References
PMID: 3095147 by Codina J., et al. Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical.
PMID: 14512443 by Niu J., et al. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.