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- Table of Contents
GNG7 Antibodies
AND GNG7 ELISA kits, GNG7 Proteins
Many biological assays use antibodies to detect GNG7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNG7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNG7 antibodies...
Designing a Western blot for GNG7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GNG7 Western Blot GuideDesigning an IHC experiment for GNG7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GNG7 IHC GuideGNG7 Infographic by Boster Bio
All GNG7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A10690-1
100 μg/vial
Cat # A10690-1
100 μg/vial
GNG7 Overview
Facts about Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7.
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7)
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) which is required for adenylyl cyclase activity in the striatum (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | GNG7 |
| Uniprot: | O60262 |
| Entrez: | 2788 |
Family
| Belongs to: |
|---|
| G protein gamma family |
Alternative Names
FLJ00058; GNGT7; guanine nucleotide binding protein (G protein), gamma 7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Molecular Weight
Mass (kDA):
7.522 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (2511219..2702694, complement) |
Tissue Specificity
Expressed in a variety of tissues. Down- regulated in pancreatic and esophageal cancer.
Subcellular Localizations
Cell membrane; Lipid-anchor; Cytoplasmic side.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Inflammation
- Autoimmunity
- Neoplasm Metastasis
- Classical Hodgkin's Lymphoma
- Uterine Cervical Neoplasm
- Head And Neck Carcinoma
- Neoplasm Invasiveness
- Carcinogenesis
- Head And Neck Neoplasms
- Malignant Neck Neoplasm
Pathways
- Keratinization
- Methylation
- Dna Hypermethylation
- Cell Death
- Pathogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNG7
bosterbio.com/bosterbio-gene-info-cards/GNG7
References
PMID: 9600093 by Shibata K., et al. Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer.
PMID: 18219292 by Ohta M., et al. Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer.