GPAA1 Antibodies

AND GPAA1 ELISA kits, GPAA1 Proteins

Many biological assays use antibodies to detect GPAA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPAA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPAA1 antibodies...

We validate the specificity of these antibodies to GPAA1 by testing them on tissues known to express GPAA1 positively and negatively. Browse below to find the GPAA1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPAA1 Infographic by Boster Bio

All GPAA1 Products

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Price

GPAA1 (NM_003801) Human Over-expression Lysate

Human

$628
Cat # LS008733
20 µg, 100 µg

Anti-GPAA1 Antibody Picoband®

Western blot analysis of GPAA1 using anti-GPAA1 antibody (A09298-1)

IHC analysis of GPAA1 using anti-GPAA1 antibody (A09298-1)

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A09298-1
100 μg/vial

GPAA1 Overview

Facts about Glycosylphosphatidylinositol anchor attachment 1 protein.

GPAA1 3D structure. Source: alphafold

Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1)

Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate.

Gene Information

Human
Gene Name:	GPAA1
Uniprot:	O43292
Entrez:	8733

Family

Belongs to:

No superfamily

Alternative Names

anchor attachment protein 1 (Gaa1p, yeast) homolog; GAA1 protein homolog; GAA1glycophosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); GPAA1P anchor attachment protein 1 homolog (yeast); GPAA1P anchor attachment protein 1 homolog; GPI anchor attachment protein 1; GPI transamidase subunit; hGAA1glycosylphosphatidylinositol anchor attachment 1 protein

Molecular Weight

Mass (kDA):
67.623 kDA

Genomic Context


Human

Location:	8q24.3
Sequence:	8; NC_000008.11 (144082634..144086216)

Tissue Specificity

Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Carcinoma
Malignant Neoplasms
Friedreich Ataxia
Malignant Neoplasm Of Breast
Ataxia
Neoplasms
Neoplasm Invasiveness
Mammary Neoplasms
Cell Invasion
Liver Carcinoma
Cardiomyopathies
Liver Neoplasms

Neurodegenerative Disorders
Trinucleotide Repeat Expansion
Head And Neck Carcinoma
Cardiac Hypertrophy
Malaria, Falciparum
Malignant Neoplasm Of Urinary Bladder
Malignant Neoplasm Of Lung

Pathways

Localization
Cell Adhesion
Endoplasmic Reticulum Localization
Translation
Long-term Memory
Dedifferentiation

PTMs

Gpi Anchoring
Phosphorylation

Glycosylation
Cleavage

Amidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPAA1

References

PMID: 9468317 by Hiroi Y., et al. Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins.

PMID: 10393431 by Inoue N., et al. Human and mouse GPAA1 (glycosylphosphatidylinositol anchor attachment 1) genes: genomic structures, chromosome loci and the presence of a minor class intron.