GPR135 Antibodies

AND GPR135 ELISA kits, GPR135 Proteins

Many biological assays use antibodies to detect GPR135, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR135 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR135 antibodies...

We validate the specificity of these antibodies to GPR135 by testing them on tissues known to express GPR135 positively and negatively. Browse below to find the GPR135 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR135 Infographic by Boster Bio

All GPR135 Products

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Anti-GPR135 Antibody

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Immunohistochemical analysis of paraffin-embedded human tonsil

Western blot analysis of lysates from NIH/3T3 cells, using GPR135 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30806
100ul

Anti-GPR135 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A15287
100ul

GPR135 Overview

Facts about G-protein coupled receptor 135.

GPR135 3D structure. Source: alphafold

G-protein coupled receptor 135 (GPR135)

Orphan receptor. Has spontaneous activity for beta- arrestin recruitment (PubMed:28827538).

Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B probably through receptor heteromerization (PubMed:28827538). .

Gene Information

Human
Gene Name:	GPR135
Uniprot:	Q8IZ08
Entrez:	64582

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 135; GPR135; HUMNPIIY20; PAFR; probable G-protein coupled receptor 135

Molecular Weight

Mass (kDA):
51.736 kDA

Genomic Context


Human

Location:	14q23.1
Sequence:	14; NC_000014.9 (59452773..59465636, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Colocalizes with ARRB2/beta-arrestin-2 in the endosome.

Diseases

Malignant Neoplasms

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR135

References

PMID: 14623098 by Fredriksson R., et al. Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.

PMID: 28827538 by Oishi A., et al. Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions.