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The activity of this receptor is mediated by G proteins that inhibit adenylyl cyclase (PubMed:16844083). May contribute to regulation of the immune system.
|G-protein coupled receptor 1 family|
|Sequence:||13; NC_000013.11 (99254713..99262498, complement)|
Expressed in midpiece of spermatozoon (at protein level) (PubMed:27572937). Most abundant in testis and spleen (PubMed:16844083). Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells (PubMed:16844083).
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.