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- Table of Contents
Facts about GRAM domain-containing protein 2A.
| Human | |
|---|---|
| Gene Name: | GRAMD2A |
| Uniprot: | Q8IUY3 |
| Entrez: | 196996 |

| Belongs to: |
|---|
| No superfamily |

GRAM domain-containing protein 2A
Mass (kDA):
40.249 kDA

| Human | |
|---|---|
| Location: | 15q23 |
| Sequence: | 15; NC_000015.10 (72159806..72197814, complement) |
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Peripheral membrane protein. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS). Anchored at the ER, PM binding is mediated via GRAM domain and phosphatidylinositol lipid interaction. Localizes to distinct EPCS than GRAMD1A.


PMID: 29469807 by Besprozvannaya M., et al. GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells.