Delphilin Antibodies

AND Grid2ip ELISA kits, Delphilin Proteins

Many biological assays use antibodies to detect Delphilin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Delphilin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Delphilin antibodies...

We validate the specificity of these antibodies to Delphilin by testing them on tissues known to express Grid2ip positively and negatively. Browse below to find the Grid2ip antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Grid2ip Infographic by Boster Bio

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GRID2IP (NM_001145118) Human Recombinant Protein

Coomassie blue staining of purified GRID2IP protein

$1249
Cat # PROTA4D2P6
20 µg

Grid2ip Overview

Facts about Delphilin.

Delphilin (Grid2ip)

Postsynaptic scaffolding protein in the Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules. .

Gene Information

Mouse
Gene Name:	Grid2ip
Uniprot:	Q0QWG9
Entrez:	170935

Family

Belongs to:

No superfamily

Alternative Names

delphilin; glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein; ionotropic, delta 2 (Grid2) interacting protein 1; ionotropic, delta 2-interacting protein 1

Molecular Weight

Mass (kDA):
132.021 kDA

Genomic Context


Mouse

Location:	5\|5 G2
Sequence:	5;

Tissue Specificity

Isoform 1 is expressed in the cerebellum, but not in the cerebral cortex. Isoform 2 is expressed in the cell body of purkinge cells of the cerebellum and weakly expressed in the cerebrum and the brainstem as well as various nuclei of the thalamus. Isoform 2 is highly expressed in the cerebral cortex than in the cerebellum. Isoform 3 is expressed in the cerebellum and cerebrum.

Diseases

Chondrosarcoma
Glioblastoma
Carcinogenesis
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Pancreas
Cell Invasion
Bladder Neoplasm
Adenocarcinoma
Melanoma
Breast Adenocarcinoma

Parathyroid Neoplasms
Oligodendroglioma
Carcinoid Tumor
Retinoblastoma
Meningioma

Pathways

Cell Division
Limb Morphogenesis
Glycosylation
Localization
Tissue Homeostasis

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Grid2ip

References

PMID: 11826110 by Miyagi Y., et al. Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit.

PMID: 16835239 by Matsuda K., et al. Characterization of the delta2 glutamate receptor-binding protein delphilin: splicing variants with differential palmitoylation and an additional PDZ domain.