GRM8 Antibodies

AND GRM8 ELISA kits, GRM8 Proteins

Many biological assays use antibodies to detect GRM8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRM8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRM8 antibodies...

We validate the specificity of these antibodies to GRM8 by testing them on tissues known to express GRM8 positively and negatively. Browse below to find the GRM8 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRM8 Infographic by Boster Bio

All GRM8 Products

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Specificity

Applications

Price

mGluR8 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from mouse brain cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1369
1 kit, containing one 96-well plate and all necessary reagents

Metabotropic Glutamate Receptor 8 (GRM8) (NM_000845) Human Over-expression Lysate

Metabotropic Glutamate Receptor 8 (GRM8) Human Over-expression Lysates NM_000845

Human

$628
Cat # LS002918
20 µg, 100 µg

GRM8 Overview

Facts about Metabotropic glutamate receptor 8.

GRM8 3D structure. Source: alphafold

Metabotropic glutamate receptor 8 (GRM8)

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.

Signaling inhibits adenylate cyclase activity. .

Gene Information

Human
Gene Name:	GRM8
Uniprot:	O00222
Entrez:	2918

Family

Belongs to:

G-protein coupled receptor 3 family

Alternative Names

FLJ41058; glutamate metabotropic receptor 8; glutamate receptor, metabotropic 8; GPRC1H; GPRC1HMGLUR8GLUR8; GRM8; metabotropic glutamate receptor 8; MGC126724; mGlu8; mGluR8

Molecular Weight

Mass (kDA):
101.741 kDA

Genomic Context


Human

Location:	7q31.33
Sequence:	7; NC_000007.14 (126438598..127252941, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Mental Disorders
Malignant Neoplasms
Nervousness
Dysequilibrium Syndrome
Cell Transformation, Neoplastic
Autistic Disorder
Malnutrition
Inflammatory Bowel Diseases
Endometrial Polyp
Intestinal Diseases
Ulcer

Neoplasms
Mammary Neoplasms
Attention Deficit Hyperactivity Disorder
Ovarian Neoplasm
Colitis
Malignant Neoplasm Of Prostate

Pathways

Nodulation
Circadian Rhythm
Nitrogen Fixation
Aging
Cognition
Pathogenesis
Localization

Oncogenesis

PTMs

Phosphorylation

Research Areas

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRM8

References

PMID: 9299241 by Scherer S.W., et al. The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1.

PMID: 9473604 by Wu S., et al. Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.