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- Table of Contents
Designing a Western blot for G-rich sequence factor 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GRSF1 Western Blot GuideDesigning an IHC experiment for G-rich sequence factor 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GRSF1 IHC GuideFacts about G-rich sequence factor 1.
Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. .
| Human | |
|---|---|
| Gene Name: | GRSF1 |
| Uniprot: | Q12849 |
| Entrez: | 2926 |

| Belongs to: |
|---|
| No superfamily |

FLJ13125; G-rich RNA sequence binding factor 1; G-rich sequence factor 1; GRSF-1
Mass (kDA):
53.126 kDA

| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (70815783..70843274, complement) |
[Isoform 1]: Mitochondrion matrix. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.; [Isoform 2]: Cytoplasm.





PMID: 8036161 by Qian Z., et al. GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element.
PMID: 23473033 by Antonicka H., et al. The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.