Transcription factor IIIA Antibodies

AND GTF3A ELISA kits, Transcription factor IIIA Proteins

Many biological assays use antibodies to detect Transcription factor IIIA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor IIIA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor IIIA antibodies...

We validate the specificity of these antibodies to Transcription factor IIIA by testing them on tissues known to express GTF3A positively and negatively. Browse below to find the GTF3A antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GTF3A Infographic by Boster Bio

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GTF3A Overview

Facts about Transcription factor IIIA.

GTF3A 3D structure. Source: alphafold

Transcription factor IIIA (GTF3A)

Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes.

It is needed for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868). Also binds the transcribed 5S RNA's (By similarity).

Gene Information

Human
Gene Name:	GTF3A
Uniprot:	Q92664
Entrez:	2971

Family

Belongs to:

No superfamily

Alternative Names

general transcription factor IIIA; TFIIIAAP2; transcription factor IIIA

Molecular Weight

Mass (kDA):
41.515 kDA

Genomic Context


Human

Location:	13q12.2
Sequence:	13; NC_000013.11 (27424619..27435823)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Down Syndrome

Pathways

Transport
Adiponectin Secretion
Cell Differentiation
Glucose Transport
Secretion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GTF3A

References

PMID: 7789179 by Arakawa H., et al. Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA.

PMID: 7622052 by Drew P.D., et al. Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA.